Biological approaches to understand schizophrenia and clinical outcomes

Antipsychotic medications are essential treatments for schizophrenia, but many people do not respond adequately or experience significant side effects. X-Lab studies the biological mechanisms that help explain why treatments work well for some individuals but not for others. Our research uses interdisciplinary approaches, including biomarkers and laboratory models derived from patients’ own cells, to examine how biological processes and individual differences influence treatment outcomes and adverse effects. Our long-term goal is to generate biologically grounded knowledge that can guide the development of more effective, personalized treatments and improve long-term clinical outcomes.