Applying genetic discoveries to psychiatric care

Despite significant advances on the discovery front of psychiatric genetics, the clinical value of these advances remains untested and unknown. A primary goal of our lab is to study how we can apply genetic findings to improve clinical care for mental illnesses.

Biological approaches to the study of psychosis and clinical outcomes

We use statistical-computational (e.g.,GWAS, multilayer network analysis) and biological (e.g., induced pluripotent stem cell or iPSC models) methods to study genetic risk variants and neurobiological mechanisms of psychosis symptoms, and clinically important outcomes such as treatment resistance.